Vital Alchemy Anafuse Review: 2024 Verdict

Anafuse, by Vital Alchemy, is a ‘dual acting’ bulking stack,’ a natural (steroid-free) yet powerful bulking/anabolic supplement. It may aid in increasing muscle mass and size, mental focus, reduce muscle fatigue, improve post-workout recovery and support overall bodybuilding efforts.

According to its grand pitch!

Despite its unique blend of ingredients—Epicatechin, HICA, Quercetin, Eriobotrya Japonica, Turkesterone, Leucine, and Vitamin D3—Anafuse delivers only 1500 ml of nutrients per serving, making it significantly weaker than some testosterone boosters. Makes you wonder how effective it truly is. 

 So does scientific evidence support its claims? Let’s take a deeper look into what Anafuse has to offer and whether it fits your needs.

Anafuse Vital Alchemy

What is Anafuse?

Anafuse positions itself as a powerful, natural anabolic supplement (bulking supplements), accelerating muscle growth (hypertrophy) without interfering with our body’s natural hormone production. It does this by optimizing natural testosterone levels through its ingredients, preserving around 80 to 90% of muscle gains, as long as you follow a smart workout and a healthy balanced diet.

It comes in a capsule format with 30 servings in a bottle and 4 recommended daily capsules for benefits.

Who Is Anafuse For?

Anafuse is typically marketed to:

  • Fitness enthusiasts
  • Bodybuilders
  • Athletes looking to enhance muscle growth, strength, and recovery. 
  • Gymgoers
  • Those looking for quicker post-workout recovery.

It may appeal to those seeking natural alternatives to traditional supplements or steroids for muscle building and performance enhancement purposes.  However, it’s important to consider individual health status and goals!

Is Anafuse Safe?

Anafuse contains ingredients like epicatechin, laxogenin, and 5a-hydroxy laxogenin, generally considered safe, but individual responses can vary. 

Individuals with high blood pressure, kidney, heart, thyroid problems, depression, cancer, smokers  and other medical conditions should approach it with caution due to potential effects on cortisol levels. The manufacturer also states these conditions on the bottle as WARNING.

Always consult a healthcare professional before starting any new supplement, especially if you have underlying health concerns or are under medical treatment.

Anafuse Features and Benefits

Anafuse by Vital Alchemy appears to be a supplement formulated to support muscle gains, protein synthesis, muscle endurance, and accelerated muscle recovery using all-natural ingredients. 

Anafuse may state to provide these benefits, following a well-rounded training plan and a healthy balanced diet is necessary. Also, the bottle states that these statements have not been evolved by the Food and Drug Administration and its not intended to diagnose, treat, cure or prevent any disease. Not a magic wand!

While it has some powerful natural ingredients that we will cover in detail shortly, its effect and result can vary by individuals. 

Here are some benefits that Anafuse may help you experience:

Promote Lean Muscle Mass

Anafuse contains Epicatechin and other ingredients that are aimed at aiding in mass gains. Specifically Epicatechin Epicatechin, a flavanol found in certain plants (cocoa, green tea), is highlighted for its antioxidant properties, aiding in decreasing Myostatin, a factor limiting muscle growth 

The study hints at cocoa-derived epicatechin as a potential treatment for age-related muscle loss. It reversed some negative markers in mice and humans, reducing myostatin and boosting follistatin, both linked to muscle growth.

However, there are more studies needed in placebo and the effect of epicatechin on humans.

Prevents Muscle Protein Breakdown

HICA, a metabolite of leucine, purportedly promotes increased protein synthesis and reduces muscle protein breakdown. Vitamin D3 is included to enhance its effectiveness as a protein synthesis amplifier for athletes.

A study explored α-hydroxyisocaproic acid (α-HICA) and its impact on muscle recovery during disuse atrophy. While it didn’t prevent muscle loss, α-HICA aided in faster recovery by maintaining higher protein synthesis rates, leading to regain muscle mass and increased protein phosphorylation after immobilization.

Speeds Up Post-Workout Recovery

As we learnt HICA may aid in speeding up recovery.

This study looked at how Quercetin (Q) supplements affect muscle recovery after intense exercise. They tested 249 people and discovered that taking 1000 mg/day of Q for up to 12 weeks helped recover muscles by lessening soreness, lowering creatine kinase levels, and reducing post-exercise oxidative stress.

Anafuse contains only 300ml of quercetin, which isn’t the optimal amount, yet combined with other ingredients like HICA, may increase its benefits on muscle recovery. Although, the package does not state the amount of HICA the product contains!

Improves Muscle Strength and Endurance

Ajuga Turkestanica (Turkesterone), known for muscle-building properties, along with Eriobotrya Japonica, Vitamin D3, and Epicatechin, are blended to increase muscle endurance. Turkesterone is considered a potent natural supplement for muscle building and recovery.

A research highlights ecdysterone’s (turkesterone falls into this category)  potential for boosting muscle growth, surpassing the effects of other known muscle-building compounds in rats. It focused on rat muscles and cells, not humans, so more research in people is needed to confirm these findings.

A large part of determining whether or not a supplement is effective for boosting testosterone and providing the stated benefits  is a thorough analysis of its ingredient profile, which we do in detail below!

There are staples found in many testosterone boosters which are necessary for it to elicit noticeable effects on this hormone. In addition to the actual ingredient list, is the need for clear indications of the amount of each of the ingredients contained in each serving of the supplement. Proprietary blends are not good enough, as the manufacturers are then not obliged to disclose this information to the consumer.

Last, but certainly not least is the overall reputation of Anafuse by persons who have consumed it in the past. Supplements with poor public feedback or ones that display a high level of dissatisfaction should clearly spell out what the product has going on for itself. Make it a practice to always search out customer feedback and reviews before purchasing any supplements.

Vital Alchemy Anafuse Ingredients

Anafuse by Vital Alchemy features six primary ingredients. While some of these components boast solid scientific support, others lack the same level of scientific proof. 

Also ithe dosage matter for maximum benefits! While the supplement lists its ingredients, the exact quantities of each remain undisclosed, which may make it less effective for some!

Vitamin D3

Most people think of sunshine when they think of vitamin D. Vitamin D is important for a number of biological functions, including the production of testosterone. AnaFuse adds vitamin D to its formula, as it has long been believed to be correlated to levels of testosterone and other male sex hormones. 

Studies have supported that vitamin D supplements can increase levels of testosterone. However, the effects of this have only been moderately shown. Vitamin D3 is usually made in our bodies when our skin has been exposed to light.

However, in winter time (or in general), some people may need additional vitamin D in the form of food like fatty fish, mushrooms,egg yolks, or supplements to reach normal levels and produce healthy levels of testosterone. 


Epicatechin is arguably one of the most promising discoveries in sports supplementation over the past two decades. It is a compound commonly found in cocoa, which exerts some unique benefits for bodybuilders.

Studied Benefits of Epicatechin: 

  • Controls Cortisol Levels: Epicatechin helps to prevent high levels of cortisol, the body’s stress hormone, from entering the blood. This is useful as high levels of cortisol have been associated with lower testosterone
  • Increased Muscle Growth: Epicatechin reduces the levels of a protein called myostatin, which prevents your muscles from growing. By suppressing this protein, epicatechin can help you to trigger a new level of muscle growth
  • Antioxidant Activity: In addition to this, epicatechin is a strong antioxidant. This can help prevent oxidative damage to the testes and helps to preserve normal testosterone synthesis.


Quercetin has been found in studies to have both antioxidant activities and help protect the cardiovascular system. It helps to reduce blood pressure and oxidative stress and has anti-inflammatory effects. 

It has also been found in some animal studies to help prevent testicular damage and prevent low testosterone levels in diabetic animals. So while the evidence is not strong, this ingredient can potentially help support overall health and wellbeing. 

HICA (5a­Hydroxy-Laxogenin)

At best, this component can be considered a plant-based steroid. It claims to possess an anabolic effect that increases the rate of protein synthesis,  coupled with cortisol suppression.

A study found that HICA, an anticatabolic compound derived from leucine, increased lean mass and reduced muscle soreness in soccer players over a 4-week period (1.5 g daily), but it didn’t enhance their physical performance.

However, take these claims with a grain of salt! Further research is needed to fully understand its long-term effects and benefits in athletes.


Although piperine alone does not have many benefits, it helps to increase the absorption of other ingredients found in the AnaFuse supplement. It is commonly combined with other ingredients and extracts which have poor absorption on their own but can significantly be enhanced by piperine.


Ajuga Turkestanica (Turkesterone), known for muscle-building properties, along with Eriobotrya Japonica, Vitamin D3, and Epicatechin, are blended to increase muscle endurance. Turkesterone is considered a potent natural supplement for muscle building and recovery. 

Yet there isn’t enough scientific research on humans backing up this statement!

Anafuse Pros and Cons

Though it does not claim to help improve any symptoms of low testosterone levels, it is likely that some improvements if hormonal optimization occurs. Here are some specific things I liked and disliked after digging deeper into Anafuse:


  • It is natural and does not contain ingredients that can adversely affect your natural testosterone production. 
  • Limited side effects
  • It takes a new approach to building muscle.
  • It can safely be stacked with a wide range of other bodybuilding supplements for even greater muscle growth potential.
  • Existing customer reviews seem to indicate that people are pleased with the product overall.


  • The lack of a manufacturer website does not lend itself to supporting the credibility of the brand or product.
  • The product is moderately expensive and can be considered a gamble purchasing from an unknown company
  • There are very few competing products that contain a similar ingredient profile, so comparisons to determine its efficacy is difficult.
  • High Price

Real Customer Anafuse Reviews 

Sometimes the best judge of a product is to know what the people thought. Here’s an overview of what customers had to say about this supplement: 

“I have been taking this for a week now and have already seen an increase in size without any water weight. My workouts have been more intense as I am finding it harder to wear myself out.” 

– Brandon A

“I took this item as directed for the two-month period… I had only gained a pound, but I increased my strength in the squat and bench by 20 pounds… Recommend this if looking for strength, not size.” 

– Pull T

‘’Powerhouse muscle builder and recovery supplement. My overall physique improved drastically after one bottle – don’t get me wrong I worked out and ate right too but this stuff had me recovering very quickly and increased muscle size. 5 stars!’’

– the seeker

‘’Great product, I’ve been taking it for years. Helps me to up my endurance, recovery and helps me to have more strength and lean muscle.’’

– Daniel S.

As you can see, there are some conflicting reviews on the product. However, most people have found somewhat of a positive benefit to using this supplement – whether that be for size, strength, or performance. 

The primary negative feedback? The cost. Many people also claim that it is a bit overpriced, which was by far the most commonly criticized element! 

Final Verdict: Does Anafuse Really Work?

Vital Alchemy’s Anafuse contains at least some ingredients that have been scientifically proven to help boost testosterone and support muscle growth. 

While it is not known just how effective these ingredients are together, most people did report at least some positive effects of using the supplement and very few (mild) side effects. 

In conclusion, we recommend this supplement to people who are willing to fork out a little extra to help their bodybuilding goals. Though you do not have much to lose, this supplement is not likely the next be-all and end-all. Ultimately, the choice is yours!